I think Oscar Isaac is a fantastic actor. I've been a fan of his ever since his turn as St. Joseph in The Nativity Story. He also had a wonderfully roguish charm as Poe Dameron in the Star Wars sequels.
Even though I am a comic book fan, I am not as familiar with Moon Knight. However, I love the haunted, hunted portrayal I see in Isaac's performance. It reminds me of Daredevil, where his power is also his curse.
There is a funky feel to this show that could either work incredibly well or become horribly tedious. Isaac's charisma held me throughout this trailer. I also like how there is something incredibly mysterious about this person's life where things are not what they seem.
I am very interested in seeing more.